Ozone is a wonder molecule to the clinicians through its potentials has not yet fully explored. It has a role in controlling bacterial, fungal and viral infections including AIDS, treating non-healing ulcers, Rheumatoid and other kinds of arthritis, different kind of skin diseases and many others.

Ozone is a tri-atomic Oxygen molecule, O3, with a different molecular structure than Oxygen. Its name is derived from the Greek word ozein meaning “to smell”. At room temperature, Ozone is a colorless gas with a characteristic odor (similar smell after thunderstorms, at high altitudes or near the sea etc).

At ground level its concentration 0.03 – 0.04 ppm. It is the atmosphere is produced by the action of UV rays and thunderstorm on the atmospheric Oxygen, but Medical Ozone is produced from pure medical grade oxygen with the help of high voltage electrical discharge. Medical ozone is a mixture of oxygen and ozone of different concentration. Medical ozone is always freshly prepared on site (in a special generator) for immediate administration. A trained physician according to the medical indication and the patient’s condition determines the exact dose of ozone.

Treating patients with ozone is not a new procedure. The first generators were developed by Werner von Siemens in Germany in 1857, and 1870 saw the first report on ozone being used therapeutically to purify the blood, by C. Lender in Germany. During World War 1, ozone was used to treat wounds, trench foot, gangrene and the effects of poison gas.

Dr. Albert Wolff of Berlin also used ozone for colon cancer, cervical cancer and decubitis ulcers in 1915. Today, after 125 years of usage, ozone therapy is a recognized modality in many nations: Germany, France, Italy, Russia, Romania, Czech Republic, Poland, Hungary, Bulgaria, Israel, Cuba, Japan, Mexico, and in five US states.

It was also used extensively to treat war wounds during World War-II. It was not popularized before, as ozone resistant materials were not used to produce ozone generators. Also, the exact concentration was unknown. Former Ozone generators are either UV light generators or plasma type generators.

Here, it was very difficult to know the precise concentration of ozone. Now with the present Corona-discharge Ozone generators, it is possible to know the exact concentration of Ozone. Also, by changing the current or the oxygen flow, Ozone concentration can be precisely modified.

Ozone has been found to be an extremely safe medical therapy, free from side effects. In a 1980 study done by the German Medical Society for Ozone Therapy, 644 therapists were polled regarding their 384,775 patients, comprising a total of 5,579,238 ozone treatments administered. There were only 40 cases of side effects noted out of this number that represents the incredibly low rate of .000007%. Ozone Therapy has been described as the safest known medical therapy.

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